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CA 19-9 blood test

Cancer antigen 19-9

In short

A typical adult CA 19-9 result is under 37 U/mL. A small rise is common and most often comes from the gallbladder, bile ducts, liver or pancreas rather than cancer. When it is used to follow a known condition, the trend over repeat tests matters most. Always read your result against the range printed on your own report.

A substance released by cells of the pancreas, bile ducts and gut.

CA 19-9 is mostly used to follow a known condition over time, most often pancreatic cancer during and after treatment. It is not a good screening test, because many other problems raise it, especially gallbladder and bile-duct problems. About 5 to 10 in 100 people make little or none, so the test does not work for them.

Is my CA 19-9 high or low?

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Typical range

ForRangeUnit
Adultsunder 37U/mL

Typical ranges for adults. Labs differ a little, so the range printed next to your result is the one to go by.

If your CA 19-9 is high

A small rise is common and most often comes from the gallbladder, bile ducts, liver or pancreas rather than cancer. When it is used to follow a known condition, the trend over repeat tests matters most.

Common reasons

  • Gallstones, or a bile duct that is blocked or inflamed
  • An inflamed pancreas (pancreatitis)
  • Liver conditions, such as hepatitis (liver inflammation) or scarring
  • Some thyroid, lung, kidney or rheumatic (joint) conditions
  • Less often: a cancer of the pancreas, bile ducts or gut, or its return

What can throw it off

A blocked bile duct can push CA 19-9 very high, and it usually falls once the blockage clears.

Questions to take to your appointment

  1. 1Is this test being used to follow something, or was it a one-off?
  2. 2Could a gallbladder or bile-duct problem explain it?
  3. 3Do my liver tests point the same way?

Read together with

Doctors rarely read CA 19-9 alone. These usually sit next to it.

Quick answers

What is the CA 19-9 blood test?

CA 19-9 (Cancer antigen 19-9): A substance released by cells of the pancreas, bile ducts and gut. CA 19-9 is mostly used to follow a known condition over time, most often pancreatic cancer during and after treatment. It is not a good screening test, because many other problems raise it, especially gallbladder and bile-duct problems. About 5 to 10 in 100 people make little or none, so the test does not work for them.

What is a normal CA 19-9 level?

For most adults, CA 19-9 is typically under 37 U/mL. Labs differ a little, so the range printed next to your result is the one to go by.

What does a high CA 19-9 mean?

A small rise is common and most often comes from the gallbladder, bile ducts, liver or pancreas rather than cancer. When it is used to follow a known condition, the trend over repeat tests matters most. Common reasons include gallstones, or a bile duct that is blocked or inflamed; an inflamed pancreas (pancreatitis); liver conditions, such as hepatitis (liver inflammation) or scarring; and some thyroid, lung, kidney or rheumatic (joint) conditions. A doctor reads it together with your other results and how you feel.

What can affect my CA 19-9 result?

A blocked bile duct can push CA 19-9 very high, and it usually falls once the blockage clears.

What should I ask my doctor about my CA 19-9?

Questions worth taking to the appointment: Is this test being used to follow something, or was it a one-off? Could a gallbladder or bile-duct problem explain it? Do my liver tests point the same way?

What this page can’t do

It reads each number on its own.

Doctors read results together — ALT with AST, ferritin with hemoglobin, TSH with free T4. A pattern says more than any single flag.

It doesn't know you.

Your age, your medicines, how you feel and your last result all change what a number means.

It doesn't remember.

Close this page and your results are gone. That's on purpose: nothing was ever sent to us.

We also make Vita: Health Coach, an app for those parts. It reads your whole report with your medicines and history in mind, answers follow-up questions in plain words, and keeps your reports in one place — for you and for the people you look after.

Vita: Health Coach on the App Store

Sources

Stuck on a word? See the medical words. How we choose our sources. More about Vita Health Coach.